Saturday, September 7, 2019

Should Companies That Fire Shoot First Essay Example for Free

Should Companies That Fire Shoot First Essay Abstract Blogging and tweeting on social media websites have pros and cons for an organization. Companies utilize blogs in order to promote their products and services along with relaying information about the company to the general public. Employers often encourage their employees to participate in various forms of social media. However, management should be aware of the risks and impact to the company’s reputation should the employee publish something that puts the company is a negative light. Keywords: blogging, social media, reputation Tesla CEO Elon Musk was right when he blogged about impending layoffs just before announcing them to company employees Blogging and tweeting can have both positive and negative impacts on the image and reputation of a company. The use of social media sites, such as Facebook and Twitter, allow employers to encourage their employees to participate in blogs in an effort to promote their brand. Some companies even use these websites as a tool to publicize the operations of the organization. By establishing and maintaining their own company website and blog, businesses are able to control the messages, both positive and negative, that are posted. (Dealbook, 2008) In an effort to intercept negative posts from the media and disgruntled employees, Tesla Motors CEO Elon Musk announced on the company’s website blog that in order to maintain positive cash flow, the organization will layoff a significant amount of its workforce. The focus of the company will be developing and improving its product line while ensuring sufficient capital. Elon Musk stated that â€Å"we had to say something to prevent articles being written that were not accurate.† (All, 2008) Cake Financial, an investing advice company, published on their company blog immediately after reducing its workforce  that it was an â€Å"extremely sad day for all of us who have to say goodbye to a group of great people.† (Dealbook, 2008) The company’s CEO, Stephen Carpenter, had drafted the blog and waited until after personally speaking with the employees before publishing the post. Carpenter wanted to make sure that there were no discrepancies as to what and why the layoffs happened. In a statement to the New York Times, Carpenter stated that â€Å"our whole company is built on the idea of transparency in investing, so that was a reason why it was important for us to do it.† (Motivateandinspire, 2009) Employees responsibility when blogging about their company Employees have a responsibility to be careful about what they publish on social media websites about their company. Privacy laws and regulations related to internet use vary by state. Depending on the nature of the content, the employee could be possibly incriminating him/herself by disclosing private information. From an employer standpoint, employee blogging could negatively impact the reputation of the business if the appropriate policies and procedures are not in place. The employer may also be at risk if the employee publishes information relating to trade secrets, financial issues, or other business related matters. (Welch Shiff) Employees should be careful if they publish negative comments about their employer, its customers, and its vendors. Employers typically have zero tolerance with this type of behavior as it can be considered a form of harassment in which the company may subject to legal ramifications (Victor, 2013) The employee risks losing their job and tainting their reputation within the workplace, which may lead to difficulty in obtaining and retaining future employment. The entertainment industry has taken advantage of the posts made on social media blogs. For example, radio stations in the Boston area make prank phone calls on the air referencing previously posted, negative comments regarding clients. The radio personality will reference the content of the blog in an effort to scare or provoke the person being pranked. While these skits may seem comical to the station listener, the effects of the actual prank call may cause harm to a company or an individual. Employees who blog about their companies do not have an ethical  responsibility to disclose their identities Employees posting comments about their employer online do not need to display their name. When employees publish positive comments about their company and its culture, others may ignore the remarks as they may consider the opinions biased. If the employee publishes their name in association with the company, the prospective customer may feel overwhelmed and smothered by knowing the same person is using social media, in addition to traditional methods of advertising, to sell their product or service. On the contrary, when employees publish negative comments about their employer, it make spark a wave of unwanted publicity for the company. Developing a policy for handling communication of sensitive issues, inside and outside, the company Deleting or retracting online posts that have been published can be impossible. Therefore, companies should develop an internet policy for handling communication of sensitive issues both inside and outside the organization. While the company may want employees to express themselves, guidelines should be established. Some of the areas that need to be addressed in a formal, written policy include: (Guerin) a. Personal use and abuse of company property and resources b. Appropriate use of organizations name c. Applicability of existing company policies i. Harassment – inappropriate comments ii. Privacy – disclosing confidential information/trade secrets/financial information/falsifying data/using company logos/using company name to promote products Employers may want to consult with an attorney or human resource specialist in order to ensure that they develop an internet policy that will help to prevent any negative public relations regarding the company and its products and services. Conclusion Since social media is becoming an essential part of the business world, companies should invest in learning about the rewards and consequences of using this source. By obtaining an understanding of the advantages and disadvantages, the company will be more equipped in handling negative (as  well as positive) public relations and have a plan for damage control for repairing their tarnished reputation. References Blogging the Layoff. (n.d.). Retrieved May 18, 2014, from http://www.itbusinessedge.com/cm/blogs/all/blogging-the-layoff/?cs=11727 Employee Posts on Facebook, MySpace, Twitter, and Blogs | Nolo.com. (n.d.). Retrieved May 18, 2014, from http://www.nolo.com/legal-encyclopedia/employee-posts-facebook-myspace-twitter-32954.html The Layoffs Will Be Blogged. (n.d.). Retrieved May 18, 2014, from http://dealbook.nytimes.com/2008/11/05/in-era-of-blog-sniping-companies-shoot-first/?_php=true_type=blogs_r=0 Newest blog topic from CEOs: Layoffs | Article | Link Grabber | Leadership training, management skills, employee motivation: ManageBetter.biz. (n.d.). Retrieved May 18, 2014, from http://www.motivateandinspire.com/ME2/Audiences/dirmod.asp?sid=04BF7B8C765E455DA06A7B6781ED0847nm=Link Grabbertype=Publishingmod=Publications::Articlemid=8F3A7027421841978F18BE895F87F791tier=4id=7C0FA76B4F4A4E53B4D97C3A4B2487ECAudID=AA83ED248A3241A5AE080E2B6DED1F5F Off-the-clock Harassment Can be Costly: What Emplo yers Need to Know. (n.d.). Retrieved May 18, 2014, from http://www.gshllp.com/60-second-memos/off-the-clock-harassment-can-be-costly-what-employers-need-to-know Tesla Motors replaces CEO, plans layoff CNET. (n.d.). Retrieved May 16, 2014, from http://www.cnet.com/news/tesla-motors-replaces-ceo-plans-layoff/ The rules of company blogging: Avoiding employee misuse and abuse. (n.d.). Retrieved May 18, 2014, from http://www.thehrspecialist.com/11584/The_rules_of_company_blogging_Avoiding_employee_misuse_and_abuse.hr?cat=sub_cat=

Friday, September 6, 2019

Treatments of Parkinson’s diseases Essay Example for Free

Treatments of Parkinson’s diseases Essay Parkinson’s disease is a neurological condition that affects the sufferer’s mobility and also the speech. It affects the central nervous system leading to a person’s inability to control body movement and also speech. It is a disease whose treatment does not intend to cure it but instead, aims at controlling its manifestation. There are various ways in which this can be done. It may involve the use of drugs, performance of surgery and also physical exercise is encouraged. It progresses gradually from the early stages with mild symptoms to later stages with severe symptoms.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The disease is as a result of lowered formation and action of dopamine which is produced by the dopaminergic neurons found in the brain. This then led to the formation of drugs that will either increase the formation or mimic the actions taken by dopamine in the brain. This was important because an increase in the levels of dopamine would lead to a reduction of the effects of the disease. All the drugs used to control the disease all include dopamine as their main active agent regardless of how it works. Depending on which class of drugs it belongs to, it may either mimic or produce dopamine.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Among the earliest forms of treatments are the anticholinergics. These were used even before the introduction of levodopa which is the most widely used drug. The anticholinergics had very mild benefits when they were compared to the harmful side effects that followed its use. The side effects include having a dry mouth, urine retention which especially occurs among men, it also causes very severe constipation and nausea. There are some other side effects that occur that are more serious and are among the major reasons why the use of these drugs has become minimal. These include confusion memory loss and hallucination (http://www.mayoclinic.com).   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The realization that the benefits realized were much less than the side effects it causes has led to the reduction of its prescription. Since some anti-depressants and antihistamine diphenhydramine tend to have the almost the same effects as the anticholinergics, some doctors prescribe them to older people who are suffering from Parkinson’s disease. Once an individual realizes that they are having hallucinations and the other severe symptoms, it is adviced that the use of the drug be stopped immediately.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Levodopa is drug that was introduced in 1967 and is currently the most commonly used drug. It is mostly addressed to as Sinemet and is used to help restore the control that one has over the muscles. It is referred to as a gold standard because it is introduced at the time when the symptoms are very mild at the onset of the disease. Once it gets into the body, it is converted inside the brain into dopamine. It therefore increases the level of dopamine that is found in the brain and counters the effects of the disease. (http://www.fdu.gov). the conversion to dopamine is what leads to the positive effects that a patient experiences when using the drug.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   It however has very serious side effects which include nausea and dyskinesias (involuntary movement). This occurs because only a small percentage of it enters the dopaminergic neurons to be transformed into dopamine in the brain. The rest of it is transformed in to dopamine in the body. It therefore becomes necessary to use cardibopa which delays the metabolism of levodopa until it reaches the dopaminergic neurons in the brain. The combination hence helps reduce the side effects caused by the drug because once the metabolism takes place only in the brain it means that the side-effects are not felt as much as when it occurs in the body.   The other problem posed by the use of this drug is that its dosage needs to be increased over time. It has also been observed that it works on and off without any explained cause as to why this happens. This makes it unreliable because its effects are not constant and at times the patient gets violent attacks while still under medication. The various side effects and unreliability of levodopa leads to the necessity to combine it with various other drugs to make it more effective. Some of these drugs can be used on their own while others actually require to be used with the levedopa-cardibopa combination.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   A cluster of drugs called dopamine agonists are usually used in a combination with the levodopa-cardibopa drugs. They can however also be used on their own. If used without the use of cardibopa-levodopa therapy, it can only be when the diseased has not progressed far and also only works well in younger adults. In other words it is used alone when the symptoms are mild and only in younger adults. This class of drugs does not produce or help in the production of dopamine but instead imitates the effects that dopamine has in the body. (http://www.mayoclinic.com). In other words, they tend to act on behalf of dopamine.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   This class of drugs include; Apokyn, Requip, Parlodel and Mirapex. Parlodel used to be administered some time back but of late its use has become less. This is because it had very serious side effects that endangered the patient more than it benefited him/her. It would cause inflammation in the lungs and/or heart valves of the user and thus would lead to further deterioration of the patients’ health. In general this class of drugs has side effects that are almost similar to those of carbidopa-levodopa but with slight differences. The effects of having involuntary movement are reduced while those of hallucinations and/or sleepiness are increased.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The drug Mirapex takes up the role of dopamine in the body as it is one of the dopamine agonists. When it is used in the absence of levodopa-cardibopa, it causes a 30% improvement in the health of the patient. When used in combination, it is able to reduce the intake of the levodopa dosage by about 25%. Requip is also a dopamine agonist that can also be used either alone or with levodopa. When used together with levodopa, it can reduce the intake of the close by around 31%. The reduction of the dosage is on top of increased benefits to the patient (http://www.fda.gov). Catechol-o-methyltransferace inhibitors which are usually abbreviated as COMT inhibitors, are used block the enzymes that break down the levodopa into dopamine even before it reaches the brain thus causing severe side effects and minimal benefits to the patient. They can be used in combination with the levodopa-cardibopa therapy. The two main COMT inhibitors are Tasmar and Entacapone. Tasmar is rarely used because of its severe impact on the health of the user. It causes severe liver damage and hence is only used as a last resort if the patient has failed to respond to any other therapy (http://www.mayoclinic.com)   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Stalevo is the result of a combination of cardibopa, levodopa and entacapone. Entacapone does not have side-effects as severe as those of tasmar and hence is preferred than tasmar. Its major side-effect is the involuntary movements experienced by the user. It works in conjunction with the cabidopa-levodopa therapy by increasing their availability. This is done by blocking the enzymes that break down the substance into dopamine until the drug is already in the brain. This then means that the effects of cabidopa-levodopa are prolonged because they occur only in the brain.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Selegiline also referred to as Eldepryl is another drug that can either be used with or without the presence of carbidopa-levodopa therapy. It works by preventing the metabolism of dopamine. It does this by slowing down the activity of one of the enzymes that metabolize dopamine. This is the monoamine oxidase B which is abbreviated as MAO-B. The use of selegiline has other positive effects like delaying the need of carbidopa-levodopa. When combined with carbidopa-levodopa it improves the effectiveness of the drug. It can however have some adverse toxic reactions when combined with Demerol which is a narcotic drug.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Apart from ingesting drugs, they can be administered through the skin through the use of a silicon-based patch. Rotigotine is a dopamine agonist drug that can be administered through the skin but can only be used in the early stages of the disease. This is called Neupro-rotigotine transdermal system. The patch requires to be changed every 24 hours. It works by stimulating the dopamine receptors in the body. Its side-effects include skin reaction where the patch is hallucinations, insomnia, drowsiness, sleep-attacks, nausea, vomiting and the most severe is the reduction in blood pressure once the person stands up (http://www.fda.gov).   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Amantadine is another drug that is used in treatment of Parkinson’s disease but its use was discovered by accident. Initially it was to be an antiviral used in the treatment of influenza and was approved as such in 1976 by Food and Drug Administration. It was however discovered to provide relief if only short term when used alone in the early stages of the Parkinson’s disease. When it is combined with carbidopa-levodopa it can be used by those in the later stages. It has side effects that mostly involve swelling of the ankles and also turning the skin color to purple (http://www.mayodinic.com).   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   In every human beings body, there is the presence of coenzyme Q10 which is produced by the mitochondria. This enzyme is used in the transport of electrons so that they can gain energy from the oxygen inhaled. This is done in the process called cellular respiration. The levels of this enzyme are very low in those suffering from Parkinson’s disease. These people can therefore benefit greatly by having more of this enzyme which can only be done by taking supplements.   This then aids in helping slows down the onset of the disease and these supplements can be brought from a pharmacist.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Apart from the use of drugs, there are various surgeries that can be used to control the effects of the disease. One of the surgeries is pallidotomy which involves the destruction of a small bit of the globus pallidus. This is because it is overactive in those suffering from Parkinson’s disease. It is done by drilling a small hole in the skull and using an electric probe to do the destruction. It can only be done when the patient is sedated but awake so as the judge his or her reactions to stimuli. It is done on one side of the brain at a time and may be done more than once if necessary. Its side effects mostly involves impaired speech (http://www.fda.gov)   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Thalamotomy is another surgical procedure used in the control of Parkinson’s disease. It is only performed on those patients who are experiencing tremors in either the hand or the arm and these tremors become too severe to the point of disabling that person. It involves the destruction of a specific group of cells that are in the thalamus in the brain. It has been found to be successful in that it reduces or completely eliminates the tremors in around 90% of those who undergo the procedure (http://www.fda.gov).   There is also the presence of a gadget that can be equalized to the pacemaker used for cardio problems and is referred to as a â€Å"brain pacemaker† (http://www.fda.gov). This is a form of therapy is referred to as Active Tremor Control Therapy. It involves the surgical implantation of an insulated wire to the brain. It is placed in the thalamus region of the brain, the subthalamic nucleus, and also the globus pallidus area of the brain. It is referred to as a neurostimulator whose main task occurs in the process of a tremor occurring. The whole system includes three components which are: lead, extension and the neurostimulator. This system is referred to as Deep Brain Stimulation because it occurs directly inside the brain. A small hole is made in the skull and through it the lead is inserted into the brain. The lead is a very thin wire that is insulated. The tip of the lead is in contact with the area that has been targeted. Once it has been implanted, it is connected to the neurostimulator by the extension which is also an insulated wire (http://minds.nih.gov). The extension passes under the skin and moves from the head, to the neck, shoulder and finally to where the neurostimulator is located. The neurotransmitter is located either under the collarbone, in the abdomen or the lower chest area just directly under the skin. The neurotransmitter involves a battery pack that sends electrical impulses to the brain. This is done through the extension and finally the lead. When the person is undergoing tremors, he or she is supposed to pass a handheld magnet over the location of the neurostimulator. The electrical impulses that are sent by the neurostimulator work by blocking the electrical signals that are the cause of the Parkinson’s disease symptoms. These are dysfunctional brain signals and they are the cause of the tremors. This procedure is preferred because it does not destroy the nerve cells and hence when one wants to stop its use it is as easy as having the system surgically removed.   This is then makes it possible for one to use it comfortably especially as it has minimal if any side effects. This system has no reported side effects as yet as it only involves inserting and removing a piece of wire in the brain. Works cited Henkel John, Parkinson’s Disease: New Treatments Slow Onslaught of Symptoms U.S Food and Drug Administration 1998. Retrieved on 22 November 2007 from http://www.fda.gov/fdac.features/19981498.html Mayoclinic.com Tools for healthier lives Parkinson’s disease Treatment April 12 2007 Retrieved on 22 November 2007 from http://www.mayoclinic.com/health/parkinsons-disease/DS00295/DSECTION=8 National Institute of Neurological Disorders and Stroke NINDS Deep Brain Stimulation For Parkinson’s Disease Information Page last update Nov 19 2007 Retrieved on 22 November 2007 from http://www.ninds.nih.gov/disorders/deep_brain_stimulation/deep_deep_stimulation.htm U.S Food and Drug Administration Neupro Patch for Parkinson’s Approved May 14 2007 Retrieved on 22 Nov 207 from http://www.fda.gov/consumer/updates/neupro051407.html

Thursday, September 5, 2019

Determinants of the Value of Computers

Determinants of the Value of Computers Market is represented as a gathering place of consumers and sellers that a good/service is obtainable purchasable by producers and purchased by shopper (Blake, 1993). Business managed by the laws of offer and demand, not restrained by management interference, regulation or grant is best as referred to as free market. A free economic system may be a system during which the distribution for resources is set solely by their offer and therefore the demand for them. this can be primarily a theoretical thought as each country, even capitalist ones, places some limitations on the possession and exchange of commodities. The market equilibrium happens at the value wherever consumers temperament to demand is capable firms temperament to produce (Begg and Ward, 2007) In alternative words the connection between the demand and provide determines the equilibrium position of a specific smart or a service within the market place wherever no economic forces area unit being generated to alter the case . For a specific smart within the market this position is alleged to be existed once theres no excess demand and excess offer. In alternative words demand ought to be capable offer. HISTORY ON COMPUTERS Computers were seen as technically superior product that were sold-out initial to its domestic market, then to alternative technically developed countries. Moment in time, its being foreign to the developing countries and that eventually made by their voters. For international trade, the long-run pattern is that the trades among countries area unit being largely influenced by product innovation (invention) and sequent diffusion. The diffusion for pc product is therefore fast and cogent that its currently become virtually not possible to finish a task within the geographic point or colleges while not the help of a pc each within the develop and developing countries. Supply and demand, in recent social science, area unit factors that area unit thought to work out value, by showing a relationship between the quantity of a given article of trade makers WHO anticipate to sell at a definite value (in alternative words supply), and therefore the quantity of that article of trade that customers area unit ready to shop for (in alternative words demand). to produce suggests that manufacturing variable amounts of a good/service that producers to be sold-out at totally different prices; normally, higher costs may lead to a larger offer. Demand refers to the amount of an honest thats requested by shoppers at any given value. in keeping with the law of demand, demand decreases because the value goes up. in an exceedingly utterly competitive economy, {the provision|the offer|the availability} of the upward-sloping offer curve and therefore the descending demand curve yields a supply and demand schedule that, in order that because the 2 curves meet at some ext ent, the equilibrium value of associate item might be got hold of. the data on offer and demand is sourced from king Marshall‘s twentieth century theories, that acknowledges the role of shoppers in value determination, instead of taking the recent theory that focuses utterly on the value for the producer as a determinant. Marshalls work reveals along the recent offer theory with newer developments directed at the utility of a artifact to the buyer. Recent theories, like indifference-curve analysis and unconcealed preference, provide additional credence to the availability and demand theories fashioned by writers of utility. the idea of physical property is vital as well: it reveals however sure product can bear a substantial increase in value if theres no equitable substitute out there, whereas alternative simply disposable merchandise cannot do therefore while not losing business to competitors. The relationship that exit among shoppers and suppliers of an honest in an exceedingly market is standard as demand and provide model within the field of social science. in an exceedingly free market, value and amount sold-out in an exceedingly market of a specific artifact like pc. In recent years, {the availability|the offer|the provision} and affordability of pc act as a big half in high demand of it and to meet the desired demand suppliers/ producers supply additional and additional pc in market. Klein (1983) DETERMINANTS OF the value OF COMPUTERS in an exceedingly FREE MARKET There area unit variety of things which might influence the demand and provide of computers and for this reason the value is while not human intervention determined from the demand-supply curve in an exceedingly demand-supply model. Some variables that influences demand for computers area unit the increasing variety of population, preferences, income etc. of these factors have an effect on the demand of computers absolutely by a right shift in demand curve that will increase value and amount of computers which can yield a shortage of computers in market. as an example, a rise in demand as a results of the result of 1 of the determinant of demand say, a rise within the population size of pc users can shift the demand curve rightward. the rise in population size is as a results of computers being employed by the general public within the less developed and therefore the developing countries that some years back computers were employed by the developed population. The result of a rise within the size of the population on value and demand amount for pc may be seen within the figure below. An increase in demand as a results of population increase can shift the demand curve rightward. That is, the initial demand curve D and provide curve S run across to supply equilibrium E with value P and amount letter of the alphabet. a rise in population influence demand to shift the demand curve rightward to try to to, taking the new equilibrium to Eo, value rises to Po and amount will increase to Qo. cyberspace result is that theres a shortage of demand diagrammatical by Z within the figure. In addition to any or all that has been mentioned the availability of computers influenced by the quantity of suppliers, price implications of the various factors of production, technology etc are going to be imperative. These 3 factors have a positive impact on offer of pcs in computer marketplace therefore we have a tendency to witness a transparent right shift in offer curve that reduces the value and will increase the amount of computers which can yield the excess of computers. An increase within the variety of producers for manufacturing computers can cause a rise in offer of computers within the market place and thus the value. Since the suppliers will currently fancy additional profit for manufacturing the artifact in question, theyll turn out additional of computers inflicting a rightward shift of the availability curve for computers. presumptuous that the initial demand and provide curves for computers area unit D and S that run across to supply equilibrium at E with value of P and amount letter of the alphabet. the resultant result of incentive to create additional profit by producers motives them to extend offer that shifts the availability curve to therefore, taking the new equilibrium to Eo. the value of computers falls to Po and amount will increase to Qo. Source: WWW.investopedia.com Finally, we have a tendency to get the whole illustration of the topical pc market if we have a tendency to merge each rightward shift of demand and provide curve of pc in marketplace along in demand-supply model. during this case, the amount will increase however the value of the pc would possibly fall or rise. For {a sure|a particular|an exact|a precise|a definite|an explicit} shift of pc demand and sure shift of pc offer {the value|the worth|the value} wont be modified however a trifle larger shift in offer curve than the certain shift can decrease the pc price. THE amendment result OF financial gain AND SUBSTITUTION ON the value OF COMPUTERS Another angle to the current issue is to seem at it from whats known as the financial gain result and substitution result of a amendment in value. Demand of a artifact, say computers, is that the amount of the artifact that customers are going to be ready to purchase at a specific value over a declared amount . Demand is influenced several factors like population, taste, income, the standard of the products or services being offered, and therefore the handiness of competitors product or services so on. These factors influencing demand may be cluster into 2, the substitution and financial gain effects. The substitution result emphasizes the amendment within the consumption (demand) of a artifact ensuing from a amendment (in the other direction) within the consumption of a second (related) artifact. as an example, a discount within the value of computers (the product in question) would create substitutes comparatively costly and therefore the shopper would demand additional of computers. In essence the amount demanded for computers would increase. The financial gain result on the opposite hand focuses on the amendment in real financial gain ensuing from a value amendment. a rise within the value of computers as an example would cause a fall within the real financial gain of the buyer. the buyer would purchase less of each smart as well as pc. Therefore the financial gain and substitution effects acts to enforce a negative relationship between value and amount demanded in an exceedingly free market. The figure below explains it. The substitution result is outlined by slippy the budget line around a hard and fast indifference curve; the financial gain result is outlined by a parallel shift of the budget line. the initial budget line is at ab and a fall within the value of pc takes it to aj. the initial equilibrium is at E with letter of the alphabet of demand pc, and therefore the final equilibrium is at E1 with Q1 of pc demanded. to get rid of the financial gain the financial gain result, we have a tendency to shift the aj to a parallel line nearer the origin till it simply touches the indifference curve that passes E. the intermediate purpose E0 divides the amount turn into a substitution result Qo-Q associated an financial gain result Q1-Q0. It may also be obtained by slippy the initial budget line ab round the indifference curve till its slope reflects the new relative costs. SUPPLY Supply is that the amount of products that producers area unit willing and ready to offer at {a cost|a value|a value} or price over a given amount of your time. With offer, 2 factors area unit vital; the temperament to produce and skill to produce. With the temperament to produce, a rise in value of a artifact offers a rise in profitableness given price. thus a rise in value provides associate incentive for producers to supply and provide additional to the market. ABILITY to produce Another issue is that the ability to produce. a rise in offer (production) is typically amid a rise in price. price of manufacturing extra units of artifact is typically high significantly once production exceeds the reserve capacity: additional labour hours would be paid overtime, so advanced technology is also needed to amass extra raw materials, etc. a rise in value provides a motivation to supply additional since {the extra|the extra} value may protect these additional prices. the availability curve is so absolutely slope, indicating that additional is provided at the next value alternative things being equal. The marketplace for computers represents that of a technology whose costs were way higher than their price of production. the value of manufacturing a pc was comparatively higher 20-30 years past. but its value was terribly high creating them terribly profitable. As the technology to supply them (computers) subtle, additional producers (manufacturers) in an effort to create profits entered into the market and provide additional computers. Existing suppliers of computers additionally increase their output due to their temperament to create additional profit. The will increase in offer can cause the availability curve of computers to shift to the proper. The suppliers of computers area unit terribly sensitive to cost. They respond quickly to costs thanks to the presence of competitors (other manufacturers). On the demand facet, the utilization of computers has become additional of necessity; folks realize it imperative to own computers in their homes and work places. Students, even those within the lower grades, need computers to try to to their work. so users or purchasers of computers area unit rather comparatively less sensitive to the value of computers. The net result of those rightward shifts in demand and provide area unit shown within the graph below: The original demand curve DD intersects with offer curve SS at value P1 and amount Q1. pc users being comparatively less sensitive to cost of pcs can increase amount demanded for computer leading to a shift in demand from DD to DD1. On the opposite hand, producers being impelled to create profit increase offer of computers into the market place shifting the availability curve from SS to SS1. The new meeting purpose of DD1 and SS1 turn out P2 and Q2 that shows a fall in value from P1 to P2 and a rise in amount demanded from Q1 to Q2 Conclusion Demand and provide area unit the key determinants within the value of computers. The ability to manage them can facilitate management the value of computers. The higher than document has highlighted factors that would management this sound on economic theories and principles from standard authors and commentators.   REFERENCES Landsburg, S (1999), value theory and applications , 4th edn. Cincinatti: South –Western faculty Publications Perloff J (2001), economics second edn. New York: Addison-Wesley Pindyck, R D. Rubinfeld (2001), economics fifth edition,Upper Saddle watercourse, New Jersey: novice Hall Begg, D. and Ward, A. ( 2007), social science for Business, second edition, ballplayer Hill Publications Hubert, H. (2004), Business and social science Klein, L. (1983), The social science of offer and Demand WEBSITES http://www.investopedia.com/university/economics/economics3.asp, Accessed 02 Dec 2010. http://www.netmba.com/econ/micro/supply-demand/, Accessed fifth Dec 2010 Read more: http://www.ukessays.com/essays/economics/demand-and-supply-and-free-market-economy-economics-essay.php#ixzz3BLYtwrDv

Wednesday, September 4, 2019

The Neurobiology of Memory and Aging Essay -- Science Scientific Essay

The Neurobiology of Memory and Aging "I lost my keys again," my mother exclaimed at dinner a few nights ago, "I really am getting old." This use of old age as a justification for memory deficits is extremely common. Many people relate old age with loss of memory and other neurobiological functions. Why is it that aging seems to go hand in hand with losing and forgetting things? Is there a neurobiological explanation for this phenomenon? It is clear to neurobiologists that aging results in a decrease in brain size as well as a decrease in the efficiency of brain functions. It has been a widely held belief that aging causes neurons to die and for the overall number of neurons to decrease as one reaches old age. Studies conducted by Dr. David Merrill refute this idea, sighting a lack of neuronal loss in the entohinal cortex after running an MRI on a healthy subject. Instead, Merill indicates that loss of neurons may occur in degenerative disorders, such as Alzheimers, but not in healthy brains. However, it remains true that some aspects of cognition do decline as age increases, such as short term and long term memory. Since these effects are not caused by a decrease in the number of neurons present, there must be another neurobiological explanation. In order to understand memory loss it is necessary to understand how memory works in a normal brain without any cognitive deficits. Memory can be separated into three distinct parts: working memory, declarative memory, and procedural memory (1). Working memory is the most short term, and it involves repeating something that someone has just said in conversation or remembering something you had just seen briefly. This part of memory does not ever become fully sto... ...mplex.. http://psych.wisc.edu/postlab/Psych733/Nadel_Moscovitch.1997.pdf 4)Nadel and Moscovitch. "Memory Consolidation, Retrograde Amnesia and the Hippocampal Complex.. http://psych.wisc.edu/postlab/Psych733/Nadel_Moscovitch.1997.pdf 5) The Symptoms of Alzheimer's. . http://www.diseases-explained.com/Alzheimers/symptomsalzheime.html 6) Greenwood. . http://sln.fi.edu/brain/nutrition/carbohydrates/brainpower.html 7) Alzheimer's Secondary Victims. . http://sites.unc.edu/error.html 8)Alipoprotein E. . http://home.mira.net/~dhs/apoe.html 9) Determining the Cause of Memory Loss in the Elderly . http://www.postgradmed.com/issues/1999/10_15_99/welsh.htm 10)Stress tied to Memory Loss . http://www.academicpress.com/inscight/04221998/grapha.htm 11)University of Kuopio, Series Reports, Department of Neurology . http://www.uku.fi/neuro/39abs.htm The Neurobiology of Memory and Aging Essay -- Science Scientific Essay The Neurobiology of Memory and Aging "I lost my keys again," my mother exclaimed at dinner a few nights ago, "I really am getting old." This use of old age as a justification for memory deficits is extremely common. Many people relate old age with loss of memory and other neurobiological functions. Why is it that aging seems to go hand in hand with losing and forgetting things? Is there a neurobiological explanation for this phenomenon? It is clear to neurobiologists that aging results in a decrease in brain size as well as a decrease in the efficiency of brain functions. It has been a widely held belief that aging causes neurons to die and for the overall number of neurons to decrease as one reaches old age. Studies conducted by Dr. David Merrill refute this idea, sighting a lack of neuronal loss in the entohinal cortex after running an MRI on a healthy subject. Instead, Merill indicates that loss of neurons may occur in degenerative disorders, such as Alzheimers, but not in healthy brains. However, it remains true that some aspects of cognition do decline as age increases, such as short term and long term memory. Since these effects are not caused by a decrease in the number of neurons present, there must be another neurobiological explanation. In order to understand memory loss it is necessary to understand how memory works in a normal brain without any cognitive deficits. Memory can be separated into three distinct parts: working memory, declarative memory, and procedural memory (1). Working memory is the most short term, and it involves repeating something that someone has just said in conversation or remembering something you had just seen briefly. This part of memory does not ever become fully sto... ...mplex.. http://psych.wisc.edu/postlab/Psych733/Nadel_Moscovitch.1997.pdf 4)Nadel and Moscovitch. "Memory Consolidation, Retrograde Amnesia and the Hippocampal Complex.. http://psych.wisc.edu/postlab/Psych733/Nadel_Moscovitch.1997.pdf 5) The Symptoms of Alzheimer's. . http://www.diseases-explained.com/Alzheimers/symptomsalzheime.html 6) Greenwood. . http://sln.fi.edu/brain/nutrition/carbohydrates/brainpower.html 7) Alzheimer's Secondary Victims. . http://sites.unc.edu/error.html 8)Alipoprotein E. . http://home.mira.net/~dhs/apoe.html 9) Determining the Cause of Memory Loss in the Elderly . http://www.postgradmed.com/issues/1999/10_15_99/welsh.htm 10)Stress tied to Memory Loss . http://www.academicpress.com/inscight/04221998/grapha.htm 11)University of Kuopio, Series Reports, Department of Neurology . http://www.uku.fi/neuro/39abs.htm

Tuesday, September 3, 2019

An Analysis of ?The Life and Murder Trial of Xwelas, a S?Klallam Woman :: essays research papers fc

Walking next to his father through the woods on a cool winter day, young Mason hears the sound of a bullet entering his father’s body. As he looks ahead, he sees his mother, Xwelas, lower a shotgun. In the essay The Life and Murder Trial of Xwelas, a S’Klallam Woman, Coll-Peter Thrush and Robert H. Keller, Jr. recall the events before, during, and after the murder of George Phillips, a Welsh immigrant killed by his native wife. Xwelas’ the life before the murder, the actions which provoked Phillips’ death, and how the trial was influenced all help to describe the unusual history that took place in the seventeenth century.   Ã‚  Ã‚  Ã‚  Ã‚  Xwelas’ had an unstable past that may have contributed to the anger toward George Phillips. In the mid-1800’s, there were several reasons that it was important to marry a person of a different race. â€Å"†¦The threat of slavery, depopulation due to disease, and the breakdown of traditional ways, could have encouraged a young Indian woman to seek relative refuge in marriage with a white man, miles from her home (272).† Xwelas married a man named Edmund Clare Fitzhugh, a native of Virginia who practiced law. After giving birth to two sons, Mason a Julius, Edmund found that home life was dull. He suddenly left for Seattle, leaving Xwelas to herself. However, she married William King Lear, an immigrant from Alabama. After bearing his son, Lear abandoned his family after learning that a relative died. He did not return for more than twenty years. Finally, Xwelas found a common laborer, much less of a public figure than her last two husbands. The authors of the essay write: â€Å"†¦As a forty-year-old woman with three children fathered by two different men, Xwelas may have been considered ‘used merchandise’ by potential white suitors and by tribal leaders looking for strategic marriage alliances. Or perhaps there may have been a romantic attraction between Xwelas and [Phillips]. For whatever reasons, Xwelas married George Phillips on 9 February 1878.† (273) Xwelas’ marriage to Phillips seems to have been the worst of her three marriages. Several accounts describe his alcoholism and violent rages. His beatings of Xwelas often drew the attention of neighbors, however, she sometimes tried to fight back, using weapons such as oars. By Christmas of 1878, she was pregnant with her fourth child. The rocky relationship status between Xwelas and George Phillips provoked the fatal events on Christmas Day.

Monday, September 2, 2019

Major League Baseball :: essays research papers

A Winning Hand In all professional athletics a team’s general manager is a huge piece of their overall success. In this particular situation we are dealing with baseball, where a team’s general manager is huge. There are some excellent general manager’s in Major League Baseball such as the Dodgers Paul Depodesta and the Red Sox Theo Epstein. But in this article the author specifically focused on the one GM who everyone that is familiar with sports knows of, the Oakland Athletics Billy Beane. Beane has always been a big time GM of the A’s Sandy Alderson. Alderson was the general manager of the Athletics back in the early 90’s when Billy Beane was just an Oakland scout. Beane has always been a part of big time free agent pick ups, trades, bring in rookies, or unloading franchise players. In 1992 while being a scout he and Alderson following an American League West title unloaded pricey free agent super stars, no wait resigned them. Now that does not sound like the B illy Beane of today. Ron Darling, Mark McGwire, Ruben Sierra, and Terry Steinbach all were given long term deals. So why to this day does Beane get rid of high priced star players rather than resign them like he and Alderson did in the past. Well maybe it’s because their decision to resign those players was merely an emotional decision, or maybe it’s because the team suffered six consecutive sub .500 seasons since all those re signings. That was chapter one of three in the Billy Beane era. Chapter two occurred a few A Winning Hand 3 years back when the A’s climbed back out of the AL West cellar and became a first place team again. Oakland now had a new GM, (Billy Beane) who succeeded alderson. Boy has he done an incredible job since acquiring that position in rank. Beane and the Athletics payroll is about $60 million, which is considered to be very small market. Billy Beane first created a star in now New York Yankee’s first baseman Jason Giambi. Giambi’s career sky rocketed in Oakland where he won the American League MVP award with Oakland. Now you would think a GM with any brains would resign a player like that immediately, not Beane. Giambi left and is now a Yankee, battling parasite sickness, and busy apologizing to the sport and fans of baseball because he used steroids.

Sunday, September 1, 2019

Meg Whitman – Ceo Ebay

Transactional leadership involves motivating and directing followers primarily through appealing to their own self-interest (Hellriegel, D. , & Slocum, J. W, Jr. 2009). In this case Meg Whitman’s leadership reflects transaction leadership through the focus on basic management process of controlling, organizing and short-term planning. Hellriegel and Slocum mentions Whitman craves for statistics and for bottom line results. Employees are cheerful and informal but are consistent in Whitman’s transactional leadership in planning, systems, numbers, and results. Whitman’s primary component of transactional leadership is viewed by prompting her employees at eBay to achieve their performance goals. Through these attributes Whitman believe this is one reason why eBay has been so successful (Hellriegel, D. , & Slocum, J. W, Jr. 2009). Authentic Leadership Authentic leadership refers to individuals who (1) know and understand themselves (2) know what they believe and value, and (3) act on their values and beliefs through open and honest communications with subordinates and others (Hellriegel, D. , & Slocum, J. W, Jr. 2009). The aspects of Whitman’s leadership that reflects authentic leadership is that she builds credibility and win the respect of her employees by encouraging and respecting diverse viewpoints. Whitman is described as a person with experience and discipline and not to be stereotype of a new economy executive. Whitman has learned that since she has been as eBay she has become a better leader, manger, and executive than when she arrived as a youngster (Hellriegel, D. , & Slocum, J. W, Jr. 2009). Whitman has provided a number of insights and perspectives on her leadership. Bay’s goal is to be the world’s most compelling commerce platform on the Internet. In meeting their goals and eBay’s goals, Whitman wants her employees to continue attracting more customers, expand the goods traded on the site, spread eBay to more global markets, making the user experience more fun, exciting, and easier, and acquiring Internet companies to become a full service retailer (Hellrie gel, D. , & Slocum, J. W, Jr. 2009). Under the authentic leadership Whitman has empowered and motivated eBay’s employees to trust and follow her leadership style. Transformational Leadership. Transformational leadership involves anticipating future trends inspiring followers to understand and embrace a new vision of possibilities, developing others to be leaders or better leaders and building organization or groups into a community of challenged and rewarded leaders (Hellriegel, D. , & Slocum, J. W, Jr. 2009). Transformational leadership style reflected in Whitman’s leadership through individualized consideration and intellectual stimulation. Individualized consideration is the degree to which the leader attends to followers’ needs, acts as a mentor or coach, and listens to followers’ concern (Hellriegel, D. & Slocum, J. W, Jr. 2009). Whitman shows individualized consideration when she decided to change course when one of her managers became ill on a business trip. She attended to her employee needs by staying by his side while he was in the ambulance on the way to the hospital until he was stabilized. Intellectual stimula tion is the degree to which the leader challenges assumptions, take risks and solicits followers’ ideas (Hellriegel, D. , & Slocum, J. W, Jr. 2009). Whitman’s transformational leadership style encourages her employees to â€Å"think outside the box† by being innovative. Meyers (2005) reference to Whitman leadership style is one who keeps a steady hand on the tiller rather than gripping and pulling hard on the levers of power. That means subtly steering an influencing relationship instead of controlling them to generate financial returns. For example, Whitman working from a cube and not from a corner office or conversing and not commanding her employees. Getting the employees to ask questions, as opposed to providing them with answers, and sharing what they have learned. Finally, understanding that the bottom line success often stems from experimenting and failing or from doing nothing when bold action seems desperately needed (Meyers, 2005). Whitman used her leadership skills to transform the company from an online auction house into a general purpose shopping destination. Her experience and discipline created a platform for global online market place where everybody’s chance to succeed is equal and to stay focused on the same goals (Hellriegel, D. , & Slocum, J. W, Jr. 2009). Bay’s goal of being the first people to turn to when they want to buy anything. eBay owns no inventory and warehouse which helps make it highly profitable. It has cleverly used email, message boards, and its virtual community to forge bonds with customers. A key element to eBay’s growth is the continuous expansion of their market place and new services to communicate around the world (Hellriegel, D. , & Slocum, J. W, Jr. 2009). eBay Employees Employees at eBay respond to Whitman’s leadership style in a positive way. Employees are cheerful and informal (Hellriegel, D. & Slocum, J. W, Jr. 2009). The employees are dedicated and goal driven they don’t talk about fun and games but about plans, systems, numbers, and results. Hellriegel and Slocum mentions one of Whitman’s managers stated: â€Å"I have numbers. I know them. They’re very clear. And the expectations are high† (2009, pg. 316). The employees of eBay also value Whitman’s opinion when the managers are struggle in making decisions. For example, the managers went to Whitman the CEO to make the financial decision on not selling certain Nazi memorabilia. The employees seem to enjoy working under Whitman’s leadership style. One of Whitman’s employee stated: â€Å"She will exert herself personally, far and above the call of duty. She makes you want to the right thing† (Hellriegel, D. , & Slocum, J. W, Jr. 2009). Whitman looks for ways to encourage the contributions and development of her employees. Whitman’s leadership qualities have lead eBay to great success and the global trading platform where anyone can trade practically anything.